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Core 01: Cellular NAD+ Regenerator
CORE 0130 servings (60 capsules)
+82% Cellular NAD+ levels in 14 days
4.96 (382 Clinical Reviews)

Core 01: Cellular NAD+ Regenerator

Target: NAD+ & Sirtuin Bioenergetics30 servings (60 capsules)
Clinical Benchmark: +82% Cellular NAD+ levels in 14 days

Clinically validated Nicotinamide Riboside (NR) + Resveratrol & Apigenin for sustained mitochondrial ATP synthesis and DNA repair.

Primary Biological Actions:
  • Restores cellular ATP energy synthesis across tissues
  • Activates SIRT1 and SIRT3 longevity sirtuins
  • Promotes mitochondrial DNA repair and resistance to stress
  • Inhibits CD38 enzyme that depletes NAD+ with age
1
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Liposomal Nicotinamide Riboside (NR-CL™)Direct cellular precursor that replenishes NAD+ pools
400 mg
Trans-Resveratrol (99% HPLC Pure)Allosteric activator of SIRT1 deacetylase longevity genes
100 mg
Liposomal Apigenin (Chamomile Extract)Potent natural CD38 inhibitor preventing NAD+ consumption
50 mg
BioPerine® Black Pepper ExtractIncreases flavonoid intestinal bioavailability by up to 320%
5 mg
Verified Protocol Feedback382 Reviews

What Practitioners Report

4.96/ 5.00
Based on 382 verified protocol reviews
All reviews from confirmed purchasers
Showing 4 of 382
September 2026

The standard my clinical patients needed

I have reviewed dozens of NAD formulations. The liposomal NR paired with an active CD38 inhibitor is the most scientifically sound approach on the market. Patient intracellular NAD assays confirm the bioavailability claim holds up.

Dr. Marcus Vance, MD
Integrative Longevity Physician, Beverly Hills
6 months on protocol
September 2026

Observable cognitive clarity within 10 days

I track biological age and wearable HRV daily. Switching from standard NMN to Core 01 produced a measurable bump in deep sleep stages and sustained afternoon focus without caffeine.

Elena R.
Biotech Founder, San Francisco
4 months on protocol
August 2026

Recovery between sessions is noticeably faster

Training six days a week at 48. Third month on Core 01 and the difference in next-day readiness is the clearest supplement effect I have tracked.

James T.
Masters Athlete, Austin
3 months on protocol
August 2026

Works well, wish the bottle lasted longer

No complaints on formulation or the published COA. Two capsules daily means a 30-day bottle goes quickly, so the subscription is effectively required. Would prefer a 60-day option.

Priya N.
Anesthesiologist, Chicago
5 months on protocol
Common Questions

Most reported effects appear between weeks 2 and 6. Biomarker shifts (NAD+, CRP, HRV) typically precede subjective changes, which is why we publish clinical benchmarks rather than promises about how you will feel.

Core 01: Cellular NAD+ Regenerator
Core 01: Cellular NAD+ Regenerator
$54.40(Save 20%)